Biotechnology

CONTRACT RESEARCH AND DEVELOPMENT

JOINT INTELLECTUAL PROPERTY DEVELOPMENT

BIOSIMILARS DEVELOPMENT

CUSTOM RECOMBINANT PROTEIN PRODUCTION – PURIFICATION – CHARACTERISATION

PROTEIN DESIGN AND ENGINEERING

BIOTECH CONSULTATION

Recombinant proteins

- production (bacterial, yeast, insect, mammalian)

- purification (LC, FPLC, HPLC – affinity, gel filtration, ion-exchange chromatography)

- characterisation (CD, MS, Fluorescence, CE, SDS/PAGE, Western, ELISA, BiaCore )

Gene-to-Protein service (from custom DNA sequence to engineered proteins)

Protein Engineering (mutagenesis, structure-based design, directed molecular evolution)

 High throughput compound screening

 Phage display selection technology (peptides, proteins, mimotope, antibody, IVE)

Cell line engineering and development

Large-scale fermentation (2-100 L) and downstream processing.

Antibody development and production (from target DNA sequence to monoclonal antibodies)

Cytokine development and production (recombinant and labelled cytokines)